I have a computational neuroscience laboratory focused on developing neuroimaging data processing algorithms for elucidating the biological course of cognitive decline in elderly individuals. My team develops novel methods for automatically delineating regions of interest in brain scans, precisely quantifying atrophy to those regions, and estimating measurement error in the delineations. We then apply the methods to imaging data from large epidemiological studies, and report findings that relate brain characteristics to susceptibility to, and progression of, late-life cognitive disorders.
View All Publications Recent Publications
- Christopher Schwarz, Evan Fletcher, Charles DeCarli, Owen Carmichael, "Fully-Automated White Matter Hyperintensity Detection With Anatomical Prior Knowledge and Without FLAIR", in "Proceedings of Information Processing in Medical Imaging (IPMI)", 2009
- Karl Beutner, Gautam Prasad, Evan Fletcher, Charles DeCarli, Owen Carmichael, "Estimating Uncertainty in Brain Region Delineations", in "Proceedings of Information Processing in Medical Imaging (IPMI)", 2009